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10.31.17

Steep Hill Genetics | Understanding Phenosight™

Steep Hill uses a unique combination of chemical and genetic tests to help identify qualities before you plant. Using our suite of analytics, we can help growers find top phenotypes. We sex test seedlings as early as the second leaf set to determine if it’s a male; we assess whether seedlings have any unique genetic markers and then use an HPLC to determine THC/CBD ratio. Once the flowers are developed we can test to determine optimum harvest time and then test matured flowers for potency once curing is complete.

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10.31.17

Why Does Each Cannabis Lab Report Total THC Differently?

Decarboxylation is the process whereby the acid cannabinoids (such as THCA) produced by the plant are heated to "activate" them by converting to the neutrals (such as THC). In the process, each acid molecule loses CO2 (carbon dioxide) which leaves as a gas. In concentrates, one can often see the bubbles during this process. Since the acid molecules lose mass (CO2 has a molar mass of 44 D), the percent by weight of ∆9THC will always be lower than the percent by weight of THCA. For THCA--->THC, the conversion results in THC (MW = 314.4 g/mol) from THCA (MW = 358.4 g/mol) so the ratio is 0.88. But that's not all that happens. In addition to losing CO2 and forming THC, THCA also forms other byproducts. In most instances, a good estimate of the total conversion efficiency is about 75%, but this will depend somewhat on temperatures and times used to decarboxylate. What is "Total THC"? The term "Total THC" does not have a well-defined meaning. It is calculated in different ways, producing very different results.

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10.31.17

Cannabis, Terpenes and the Entourage Effect

Any given terpene can be found to exist in an amazing variety of different plants. For instance, ß-Caryophyllene is found in black pepper, cloves, some cannabis sativa strains, rosemary and hops. Cannabinoids were originally believed to only exist in family Cannabaceae, but have since been found in other families of plants such as family Linaceae (Flax), and Asteraceae (Echinaceae and Helichrysum). About a dozen plants containing CBD have been identified. The variety of plants producing the CBG-A needed to produce other cannabinoids is unknown at this point, the search is just starting. Not surprisingly, the heated/vaporized smoke of cannabis contains up to 50% terpenes, with cannabinoids normally accounting for 10-20% and the other terpenes accounting for another 10-30%.

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10.31.17

What is Residual Solvent Analysis?

In the manufacturing of cannabis concentrates and extracts, solvents (water, butane, carbon dioxide, ethanol, etc.) are used to extract the active ingredients from plant material to produce a resinous, sometimes glassy product. Steep Hill regularly tests solvent extractions for residual solvents, helping manufacturers ensure the quality of their product, and empowering consumers with greater awareness of the composition of the products they are consuming.

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10.31.17

Cannabinol (CBN): A Sleeping Synergy

Many who have heard of the cannabinoid Cannabinol (CBN) have a negative impression of the compound, as it is typically believed to be a degraded compound that appears in old, poorly stored cannabis. However, this bleak perspective is not entirely accurate.

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10.31.17

Microbial Contaminant Remediation, Molds and Fungi in Cannabis

As the cannabis industry emerges, many questions surrounding the safety and efficacy of cannabis remain unanswered. In contrast with almost all other industries in the United States, where products are grown for human consumption and/or medical use, the cannabis industry has virtually no guidelines, limitations, or quality assurance mechanisms in place to protect its employees and consumers, aside from those provided by third parties such as Steep Hill. As a result, the quality of cannabis can vary widely from season to season, farm to farm, between growers, collective dispensaries, and even day to day within the same collective. An industry wide lack of standardized practices and remediation strategies virtually ensures that this will continue. This writeup aims to help providers begin a path towards effective quality assurance over the medicinal products they provide to patients, and become leaders in the industry in the process.

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10.31.17

THCV: The Sports Car of Cannabinoids

The cannabis plant makes most cannabinoids, like THC, CBD, and CBC, out of CBG-A. CBGV-A appears in the plant much more rarely, and forms similar cannabinoids, except they only have 3 carbon tails (c3), instead of the more common 5 carbon tail (c5). These 3 carbon tailed cannabinoids are referred to as ‘varins’, such that the c3 version of THC (THC-c5) is named Tetrahydrocannabivarin (THC-c3).

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05.13.18

Steep Hill and Eybna Launch DELTA

Jmîchaeĺe Keller, President and CEO of Steep Hill and Nadav Eyal, Co-founder and CEO of Eybna Technologies Ltd, announce the companies have jointly launched Delta™, producing custom terpene formulations for incorporation into cannabis-derived products. Delta™ enables brands and manufacturers to customize and augment the terpene experience to realize a best-use profile for their customers. Initially, Delta™ will be available in California, Washington, New Mexico, Hawaii, and Maryland, with numerous states and countries coming on-line in 2018.

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05.13.18

Steep Hill Rapidly Expands Its Global Footprint

In addition to Canada, Steep Hill has expanded into Mexico and six new European Union markets offering full service cannabis quality assurance to the strategic Mexican and European markets as they open and legalize cannabis for the benefit of their patients. The testing umbrella now includes Steep Hill Mexico, Steep Hill Germany, Steep Hill Spain, Steep Hill France, Steep Hill Italy, Steep Hill Switzerland, and Steep Hill United Kingdom. In unregulated markets, Steep Hill will be on the ground supporting the legalization and regulatory process, helping regulators avoid making the mistakes that other jurisdictions have made in the past. In the role as the industry standard, Steep Hill can leverage our world-class scientific knowledge and state of the art technology to help regulators provide confidence in the marketplace that the cannabis patients consume, are both safe and effective.

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11.15.18

Smoke Contamination of Cannabis

If you can smell smoke in your garden or see a haze of smog on the ridgelines near your property, you are likely impactedby the wildfires in California.

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